5 month old kitten in heat ;(?

I adopted 2 kittens (brother and sister) from a rescue organization about a month ago they are 5 months now. I have an apt in 3 weeks to have them spayed and neutered my Vet wanted to wait till they were 6 months old. I also have a 5 1/2 year old neutered male tabby and 2 fixed male dogs. Problem, the little girl went into heat 2 days ago. I have never experienced this and I am a little upset. I have been keeping her in a spare bedroom when I can't be around as she is upsetting the other "boys" even the dogs (weird). My older male cat actually seems angry at her when she comes around and her brother.... just licks her and (fingers crossed) has not been all that interested. My Vet can't fit me in any earlier so I am left with this situation. I have questions

1) after her heat cycle passes will she return to (normal) and will my other cat play with her again?

2) I have a clean house and I have read that cats male and female will spray when a female is in heat....how would I know if this is happening..before i smell it? do you see it?

3) I feel horrible that she has to experience this...is there anything that I can do to help her?

Thank you

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